Length, protein–protein interactions, and complexity
نویسندگان
چکیده
منابع مشابه
Length, Protein-Protein Interactions, and Complexity
The evolutionary reason for the increase in gene length from archaea to prokaryotes to eukaryotes observed in large scale genome sequencing efforts has been unclear. We propose here that the increasing complexity of protein-protein interactions has driven the selection of longer proteins, as longer proteins are more able to distinguish among a larger number of distinct interactions due to their...
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The question of how one should decide among competing explanations of data is at the heart of the scientific enterprise. Quantitative methods of selecting among models have been advanced over the years without an underlying theoretical framework to guide the enterprise and evaluate new developments. In this paper, we show that differential geometry provides a unified understanding of the model ...
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ژورنال
عنوان ژورنال: Physica A: Statistical Mechanics and its Applications
سال: 2005
ISSN: 0378-4371
DOI: 10.1016/j.physa.2004.11.021